By The Associated Press

March Madness has truly begun! By the end of the first round, a trio of top seeds were already gone — No. 1 seed Purdue, No. 2 seed Arizona and No. 4 seed Virginia — and gone with them were millions of busted brackets.

Here is what to know going into the weekend of the NCAA Tournament, including the favorites and underdogs as well as key games:


The top four seeds in the tournament were given to Alabama, Houston, Kansas and Purdue. Each had its share of headaches to set up what is already proving to be a chaotic tournament and the Boilermakers were the first to fall, ousted in a first-round stunner. Here is the latest from each region:

EAST REGION: The Boilermakers got a No. 1 seed for the fourth time, but Purdue was dumped by Fairleigh Dickinson in a near-historic upset. The region appears to be wide open for the likes of No. 2 seed Marquette, Duke, Michigan State and more.

SOUTH REGION: Alabama, led by coach Nate Oats in a challenging season, is a No. 1 seed for the first time behind SEC player of the year Brandon Miller, who has armed security on hand after being the subject of threats. The Crimson Tide opened the tourney with an easy win. Potential hurdles could include Baylor, Missouri and Creighton. Princeton or Furman, anyone?

MIDWEST REGION: Houston got a top seed and won its opener but All-American Marcus Sasser is hobbled by a groin injury. Potential hurdles could include No. 2 seed Texas, which advanced to face surprising Penn State.No. 3 seed Xavier held off Kennesaw State in its opener.

WEST REGION: Kansas is the top seed in a stacked region and the Jayhawks faced a tantalizing second-round matchup against Arkansas. Kansas is without coach Bill Self, who is recovering from a heart procedure. No. 2 seed UCLA looked every bit a title contender in its opener, No. 3 Gonzaga advanced and a juicy 4-5 matchup pitted UConn against Saint Mary’s in the second round.


The unforgettable moments are piling up already.

Princeton used a late run to earn its first NCAA Tournament win in 25 years by ousting No. 2 seed Arizona. Furman celebrated its first tourney appearance since 1980 with a win over No. 4 seed Virginia on a deep 3-pointer by JP Pegues with 2.4 seconds left.

Then came 16-seed Fairleigh Dickinson’s win over Purdue as the 22 1/2-point underdog stifled 7-4 center Zach Edey to advance and join UMBC in the record books.

At the player level, Texas A&M had no answer for the 3-point acumen of Penn State’s Andrew Funk, who made 8 of 10 to help send the Aggies home. Kam Jones of Marquette had a stunning second-half scoring binge to lead the Golden Eagles to a win in their opener.


No. 4 Tennessee (24-10) vs. No. 5 Duke (27-8), Saturday, 2:40 p.m. ET (CBS)

The Blue Devils have won 10 straight under first-year coach Jon Scheyer with Jeremy Roach matching his career-high with 23 points in each of his last two games. The Volunteers blew an 18-point lead and survived a challenge from Louisiana-Lafayette in the opening round.

No. 7 Missouri (25-9) vs. No. 15 Princeton (22-9), Saturday, 6:10 p.m. ET (TNT)

Princeton grabbed its first tourney win in 25 years by using a late 9-0 run to upset No. 2 seed Arizona. The other Tigers ended a six-game tournament skid with their first win in the Big Dance since beating Clemson in the first round in 2010.

No. 1 Houston (32-3) vs. No. 9 Auburn (21-12), Saturday, 7:10 p.m. ET (TBS)

The top-seeded Cougars could be without star guard Marcus Sasser, an All-American who appreared to have reinjured a groin in the opening round against Northern Kentucky. Either way, the Cougars will have the find a way to slow Johni Broome, who was unstoppable in the Tigers’ opening win.

No. 2 Texas (27-8) vs. No. 10 Penn State (23-13), Saturday, 7:45 p.m. (CBS)

The Longhorns will have to hope Andrew Funk falls into some kind of, well, funk, for the Nittany Lions. His barrage of 3s helped Penn State earn its first NCAA Tournament win in 22 years. Texas, under interim coach Rodney Terry, routed Colgate in the first round.