Diane Cress, Wayne State University

Tau ntau lub hlis thaum lub caij ntuj sov xyoo 2022, kuv tus dev Scout ntuav thaum 3 teev sawv ntxov yuav luag txhua hnub. Yog tias koj muaj dev, koj paub lub suab. Thiab txhua zaus, nws gobbled nws mess ua ntej kuv mus txog rau nws, ua rau kev kuaj mob ntawm qhov ua rau nyuaj.

Cov kws kho tsiaj thiab kuv thaum kawg tau txiav txim siab ntawm kuv cov hydrangeas ua qhov teeb meem - tab sis khaws Scout kom deb ntawm lawv tsis ua haujlwm. Nws pib zoo li nkees txhua lub sijhawm - muaj kev txhawj xeeb heev hauv ib tus menyuam dev uas muaj daj daj Lab.

Ces muaj ib hnub Scout ntuav ib tug hairball - tab sis tsis yog ib tug hairball. Hauv cov dev, cov plaub hau ib txwm kis tau yooj yim los ntawm kev zom zaub mov, tab sis cov plaub hau no tau qhwv ib ncig ntawm lub ntsej muag brillo uas loj dhau mus. Thaum cov khoom txawv teb chaws no raug tshem tawm, qhov ntuav thaum hmo ntuj xaus. Scout tseem xav tau kev kho mob, txawm li cas los xij, rau qhov sib txawv thiab xav tsis thoob: Cov khoom tau cuam tshuam ib kauj ruam hauv nws lub cev qhov nqus ntawm vitamin B12. B12 yog ib qho tseem ceeb ntawm cov khoom noj uas cuam tshuam rau kev ua haujlwm ntawm cov qe ntshav, paj hlwb thiab ntau lwm cov txheej txheem tseem ceeb hauv lub cev.

Kuv yog ib tug kws noj zaub mov, thiab Kuv qhia zaub mov thiab zaub mov science rau cov tub ntxhais kawm ntawv qib siab, tab sis tseem kuv nco B12 tsis txaus uas ua rau kuv tus menyuam dev qaug zog. Cov kws kho mob tuaj yeem yooj yim ua qhov muag tsis pom hauv tib neeg - txawm tias B12 tsis txaus yog ib qho teeb meem kev noj qab haus huv uas cuam tshuam rau qhov kwv yees. 6% mus rau 20% ntawm cov neeg Asmeskas.

B12 tsis tshua muaj nyob rau hauv cov zaub mov, thiab nws tsuas pom muaj nyob rau hauv cov khoom noj los ntawm cov tsiaj. Hmoov zoo, tib neeg xav tau xwb 2.4 micrograms ntawm B12 txhua hnub, uas yog sib npaug rau ib kaum-millionth ntawm ib ooj - ib tug heev, tsawg heev. Yog tias tsis muaj B12 txaus hauv lub cev, tag nrho kev noj qab haus huv thiab lub neej zoo raug cuam tshuam.

Ib qho nyiaj siv ua haujlwm ntawm cov khoom noj uas muaj B12, suav nrog oysters, ntses, qe, nqaij liab thiab ntau dua.
Ib qho khoom noj uas muaj vitamin B12 nplua nuj - tag nrho cov no los ntawm cov tsiaj. photka/iStock ntawm Getty Images Plus

Cov tsos mob thiab cov tsos mob

Ib qho tsos mob tseem ceeb ntawm B12 tsis txaus yog qaug zog - ib theem ntawm kev nkees lossis qaug zog tob heev uas cuam tshuam rau kev ua neej nyob txhua hnub.

Lwm cov tsos mob yog neurological thiab tej zaum yuav muaj xws li tingling nyob rau hauv lub extremities, tsis meej pem, nco tsis tau, kev nyuaj siab thiab nyuaj rau kev sib npaug. Ib txhia ntawm no tuaj yeem nyob ruaj khov yog tias tsis muaj vitamin tsis txaus.

Txawm li cas los xij, vim tias tuaj yeem muaj ntau yam ua rau cov tsos mob no, cov kws kho mob yuav saib tsis taus qhov muaj B12 tsis txaus thiab tsis tuaj yeem tshuaj xyuas nws. Tsis tas li ntawd, kev noj zaub mov zoo yuav zoo li txiav txim siab tsis muaj vitamin deficiency. Cov ntaub ntawv hauv lub ntsiab lus: Vim kuv paub Scout kev noj zaub mov zoo, kuv tsis xav txog qhov tsis txaus B12 los ntawm nws qhov teeb meem.

Yuav ua li cas B12 absorbed

Kev tshawb fawb pom tseeb tias cov neeg uas noj cov zaub mov uas cog qoob loo yuav tsum tau noj cov tshuaj B12 nyob rau hauv cov nyiaj feem ntau muab los ntawm standard multivitamin. Txawm li cas los xij, ntau pua lab tus neeg Asmeskas uas haus B12 kuj tseem yuav muaj kev pheej hmoo vim tias muaj cov xwm txheej uas tuaj yeem cuam tshuam lawv lub cev kev nqus ntawm B12.

B12 absorption yog a complex multistep txheej txheem uas pib hauv qhov ncauj thiab xaus ntawm qhov kawg ntawm txoj hnyuv me. Thaum peb zom, peb cov zaub mov tau tov nrog qaub ncaug. Thaum cov zaub mov nqos, ib yam khoom hauv qaub ncaug hu ua R-cov protein - cov protein uas tiv thaiv B12 los ntawm kev puas tsuaj los ntawm plab acid - mus rau lub plab nrog rau cov zaub mov.

Cov hlwb tshwj xeeb hauv lub plab hauv ob sab phlu, hu ua parietal cells, tso ob yam khoom tseem ceeb rau kev nqus B12. Ib qho yog plab acid - nws cais cov zaub mov thiab B12 sib nrug, tso cai rau cov vitamin khi rau cov qaub ncaug R-protein. Lwm yam khoom, hu ua intrinsic factor, sib tov nrog lub plab cov ntsiab lus thiab mus nrog lawv mus rau hauv thawj feem ntawm cov hnyuv - lub duodenum. Ib zaug hauv duodenum, kua txiv pancreatic tso tawm B12 los ntawm R-protein thiab muab nws mus rau qhov tseem ceeb. Qhov kev sib koom ua ke no tso cai rau B12 nkag mus rau hauv cov hlwb, qhov uas nws tuaj yeem pab tswj cov hlab ntsha thiab tsim cov qe ntshav liab noj qab haus huv.

B12 tsis muaj peev xwm feem ntau cuam tshuam nrog kev tawg ntawm ib lossis ntau qhov ntawm cov ntsiab lus no ntawm txoj kev nqus.

Dr. Darien Sutton piav qhia cov tsos mob ntawm B12 tsis txaus nyob rau lub Kaum Ob Hlis 2021 ntu ntawm ABC TV yeeb yam 'Good Morning America.'

Kev pheej hmoo rau B12 deficiency

Yog tsis muaj qaub ncaug, B12 yuav tsis khi rau cov qaub ncaug R-protein, thiab lub cev muaj peev xwm nqus tau nws inhibited. Thiab muaj ntau pua qhov sib txawv tshuaj uas yuav ua rau lub qhov ncauj qhuav, ua rau cov qaub ncaug tsawg dhau lawm. Lawv suav nrog opioids, inhalers, decongestants, antidepressants, tshuaj ntshav siab thiab tshuaj benzodiazepines, zoo li Xanax, siv los kho kev ntxhov siab.

Peb pawg kawg nkaus ib leeg suav tau yooj yim 100 lab tshuaj nyob hauv Asmeskas txhua xyoo.

Lwm qhov ua rau muaj peev xwm ua rau B12 tsis muaj peev xwm yog qhov qis hauv plab acid. Ntau pua lab tus neeg Asmeskas noj tshuaj tiv thaiv kab mob uas txo ulcer-ua rau plab acids. Cov kws tshawb fawb tau txuas ruaj khov rau kev siv cov tshuaj no B12 deficiency - txawm tias qhov ua tau tej zaum yuav tsis tshaj qhov xav tau ntawm cov tshuaj.

Kev tsim cov plab acid kuj tuaj yeem txo nrog kev laus. Ntau tshaj 60 lab tus tib neeg hauv Asmeskas yog muaj hnub nyoog tshaj 60 xyoo, thiab qee qhov 54 lab muaj hnub nyoog tshaj 65 xyoo. Cov pejxeem no ntsib kev pheej hmoo siab B12 tsis txaus - uas tej zaum yuav nce ntxiv los ntawm kev siv cov tshuaj txo cov kua qaub.

Kev tsim cov kua qaub hauv plab thiab cov khoom siv hauv lub cev los ntawm cov hlwb tshwj xeeb parietal hauv plab yog qhov tseem ceeb rau kev nqus B12. Tab sis kev puas tsuaj rau lub plab hauv ob sab phlu tuaj yeem tiv thaiv kev tsim tawm ntawm ob qho tib si.

Nyob rau hauv tib neeg, impaired plab hauv ob sab phlu stems los ntawm gastric phais, mob o los yog pernicious anemia - ib qho kev kho mob uas ua rau qaug zog thiab cov npe ntev ntawm lwm cov tsos mob.

Lwm qhov ua txhaum ntawm B12 tsis txaus yog qhov tsis txaus pancreas ua haujlwm. Kwv yees li ib feem peb ntawm cov neeg mob uas muaj kab mob pancreas tsis zoo txhim kho qhov tsis muaj B12.

Thiab thaum kawg, Metformin, tshuaj siv los ntawm ib puag ncig 92 lab Americans kho mob ntshav qab zib hom 2, tau txuam nrog B12 tsis txaus rau xyoo lawm.

Kev kho mob rau B12 deficiency

Txawm hais tias qee tus kws kho mob niaj hnub ntsuas B12 thiab lwm qib vitamin, qhov kev kuaj xyuas zoo ib txwm suav nrog tsuas yog suav cov ntshav suav tag nrho thiab cov txheej txheem metabolic, tsis suav qhov ntsuas B12. Yog tias koj muaj cov tsos mob tshwm sim ntawm B12 tsis txaus thiab tseem muaj ib qho ntawm cov kev pheej hmoo saum toj no, koj yuav tsum mus ntsib kws kho mob kom kuaj. Kev ua haujlwm hauv chaw kuaj mob kom raug thiab sib tham nrog tus kws kho mob yog qhov tsim nyog los tshawb pom lossis txiav txim seb puas muaj qib B12 tsis txaus tuaj yeem ua si.

Nyob rau hauv rooj plaub ntawm kuv tus dev Scout, nws cov tsos mob ua rau tus kws kho tsiaj ua ob qhov kev kuaj ntshav: ua tiav cov ntshav suav thiab kuaj B12. Cov no kuj yog qhov pib zoo rau tib neeg. Scout cov tsos mob tau ploj mus tom qab ob peb lub hlis ntawm kev noj cov tshuaj B12 qhov ncauj uas tseem muaj ib daim ntawv nquag ntawm B vitamin folate.

Hauv tib neeg, hom kev kho mob thiab qhov ntev ntawm kev rov zoo yog nyob ntawm qhov ua rau thiab qhov hnyav ntawm B12 tsis txaus. Kev rov zoo tag nrho tuaj yeem siv sijhawm txog ib xyoos tab sis ua tau zoo heev nrog kev kho kom tsim nyog.

Kev kho mob rau B12 deficiency tuaj yeem ua qhov ncauj, thov hauv qab tus nplaig lossis muab los ntawm lub qhov ntswg, lossis nws yuav xav tau ntau hom kev txhaj tshuaj. Ib qho B12 ntxiv lossis sib npaug ntawm cov vitamin yuav txaus los kho qhov tsis txaus, raws li nws yog rau Scout, tab sis nws yog qhov zoo tshaj los ua haujlwm nrog tus kws kho mob kom kuaj xyuas thiab kho kom raug.

Diane Cress, Associate Professor of Nutrition and Food Science, Wayne State University

Tsab ntawv xov xwm no tau muab tshaj tawm los ntawm lub sib tham raws li Tsab Ntawv Tso Cai Muab Tso Cai. Nyeem qhov thawj tsab xov xwm.